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Discovery of 3,5-bis(trifluoromethyl)benzyl L-arylglycinamide based potent CCR2 antagonists.
Yang L, Zhou C, Guo L, Morriello G, Butora G, Pasternak A, Parsons WH, Mills SG, MacCoss M, Vicario PP, Zweerink H, Ayala JM, Goyal S, Hanlon WA, Cascieri MA, Springer MS. Yang L, et al. Among authors: zweerink h. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3735-9. doi: 10.1016/j.bmcl.2006.04.045. Epub 2006 May 15. Bioorg Med Chem Lett. 2006. PMID: 16698264
CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells.
Singer II, Scott S, Kawka DW, Chin J, Daugherty BL, DeMartino JA, DiSalvo J, Gould SL, Lineberger JE, Malkowitz L, Miller MD, Mitnaul L, Siciliano SJ, Staruch MJ, Williams HR, Zweerink HJ, Springer MS. Singer II, et al. Among authors: zweerink hj. J Virol. 2001 Apr;75(8):3779-90. doi: 10.1128/JVI.75.8.3779-3790.2001. J Virol. 2001. PMID: 11264367 Free PMC article.
Glycolipids as host resistance stimulators.
Ponpipom MM, Hagmann WK, O'Grady LA, Jackson JJ, Wood DD, Zweerink HJ. Ponpipom MM, et al. Among authors: zweerink hj. J Med Chem. 1990 Feb;33(2):861-7. doi: 10.1021/jm00164a062. J Med Chem. 1990. PMID: 2299649
63 results