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Relevance of TNBS-colitis in rats: a methodological study with endoscopic, histologic and Transcriptomic [corrected] characterization and correlation to IBD.
Brenna Ø, Furnes MW, Drozdov I, van Beelen Granlund A, Flatberg A, Sandvik AK, Zwiggelaar RT, Mårvik R, Nordrum IS, Kidd M, Gustafsson BI. Brenna Ø, et al. Among authors: zwiggelaar rt. PLoS One. 2013;8(1):e54543. doi: 10.1371/journal.pone.0054543. Epub 2013 Jan 31. PLoS One. 2013. PMID: 23382912 Free PMC article.
NRF2 drives an oxidative stress response predictive of breast cancer.
Wolowczyk C, Neckmann U, Aure MR, Hall M, Johannessen B, Zhao S, Skotheim RI, Andersen SB, Zwiggelaar R, Steigedal TS, Lingjærde OC, Sahlberg KK, Almaas E, Bjørkøy G. Wolowczyk C, et al. Free Radic Biol Med. 2022 May 1;184:170-184. doi: 10.1016/j.freeradbiomed.2022.03.029. Epub 2022 Apr 2. Free Radic Biol Med. 2022. PMID: 35381325 Free article.
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.
Zwiggelaar RT, Lindholm HT, Fosslie M, Terndrup Pedersen M, Ohta Y, Díez-Sánchez A, Martín-Alonso M, Ostrop J, Matano M, Parmar N, Kvaløy E, Spanjers RR, Nazmi K, Rye M, Drabløs F, Arrowsmith C, Arne Dahl J, Jensen KB, Sato T, Oudhoff MJ. Zwiggelaar RT, et al. Sci Adv. 2020 Sep 11;6(37):eabc0367. doi: 10.1126/sciadv.abc0367. Print 2020 Sep. Sci Adv. 2020. PMID: 32917713 Free PMC article.
Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection.
Parmar N, Burrows K, Vornewald PM, Lindholm HT, Zwiggelaar RT, Díez-Sánchez A, Martín-Alonso M, Fosslie M, Vallance BA, Dahl JA, Zaph C, Oudhoff MJ. Parmar N, et al. Among authors: zwiggelaar rt. PLoS Pathog. 2021 Mar 31;17(3):e1009476. doi: 10.1371/journal.ppat.1009476. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33788902 Free PMC article.
A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation.
Ostrop J, Zwiggelaar RT, Terndrup Pedersen M, Gerbe F, Bösl K, Lindholm HT, Díez-Sánchez A, Parmar N, Radetzki S, von Kries JP, Jay P, Jensen KB, Arrowsmith C, Oudhoff MJ. Ostrop J, et al. Among authors: zwiggelaar rt. Front Cell Dev Biol. 2021 Jan 21;8:618552. doi: 10.3389/fcell.2020.618552. eCollection 2020. Front Cell Dev Biol. 2021. PMID: 33575256 Free PMC article.