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Page 1
Multipurpose Prevention Approaches with Antiretroviral-Based Formulations.
Jean-Pierre N, Barnable P, Kizima L, Rodríguez A, Seidor S, Cooney ML, Clark MR, Doncel GF, Robbiani M, Zydowsky TM, Teleshova N, Fernández-Romero JA. Jean-Pierre N, et al. Among authors: zydowsky tm. Antimicrob Agents Chemother. 2015 Nov 23;60(2):1141-4. doi: 10.1128/AAC.02468-15. Print 2016 Feb. Antimicrob Agents Chemother. 2015. PMID: 26596943 Free PMC article.
The nonnucleoside reverse transcriptase inhibitor MIV-150 in carrageenan gel prevents rectal transmission of simian/human immunodeficiency virus infection in macaques.
Singer R, Derby N, Rodriguez A, Kizima L, Kenney J, Aravantinou M, Chudolij A, Gettie A, Blanchard J, Lifson JD, Piatak M Jr, Fernández-Romero JA, Zydowsky TM, Robbiani M. Singer R, et al. Among authors: zydowsky tm. J Virol. 2011 Jun;85(11):5504-12. doi: 10.1128/JVI.02422-10. Epub 2011 Mar 16. J Virol. 2011. PMID: 21411526 Free PMC article.
An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques.
Kenney J, Aravantinou M, Singer R, Hsu M, Rodriguez A, Kizima L, Abraham CJ, Menon R, Seidor S, Chudolij A, Gettie A, Blanchard J, Lifson JD, Piatak M Jr, Fernández-Romero JA, Zydowsky TM, Robbiani M. Kenney J, et al. Among authors: zydowsky tm. PLoS One. 2011 Jan 5;6(1):e15835. doi: 10.1371/journal.pone.0015835. PLoS One. 2011. PMID: 21246052 Free PMC article.
Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge.
Fernández-Romero JA, Abraham CJ, Rodriguez A, Kizima L, Jean-Pierre N, Menon R, Begay O, Seidor S, Ford BE, Gil PI, Peters J, Katz D, Robbiani M, Zydowsky TM. Fernández-Romero JA, et al. Among authors: zydowsky tm. Antimicrob Agents Chemother. 2012 Jan;56(1):358-68. doi: 10.1128/AAC.05461-11. Epub 2011 Nov 7. Antimicrob Agents Chemother. 2012. PMID: 22064530 Free PMC article.
A single dose of a MIV-150/Zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use.
Kenney J, Singer R, Derby N, Aravantinou M, Abraham CJ, Menon R, Seidor S, Zhang S, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Fernández-Romero JA, Zydowsky TM, Robbiani M. Kenney J, et al. Among authors: zydowsky tm. AIDS Res Hum Retroviruses. 2012 Nov;28(11):1476-84. doi: 10.1089/aid.2012.0087. Epub 2012 Jul 30. AIDS Res Hum Retroviruses. 2012. PMID: 22737981 Free PMC article.
The nonnucleoside reverse transcription inhibitor MIV-160 delivered from an intravaginal ring, but not from a carrageenan gel, protects against simian/human immunodeficiency virus-RT Infection.
Aravantinou M, Singer R, Derby N, Calenda G, Mawson P, Abraham CJ, Menon R, Seidor S, Goldman D, Kenney J, Villegas G, Gettie A, Blanchard J, Lifson JD, Piatak M Jr, Fernández-Romero JA, Zydowsky TM, Teleshova N, Robbiani M. Aravantinou M, et al. Among authors: zydowsky tm. AIDS Res Hum Retroviruses. 2012 Nov;28(11):1467-75. doi: 10.1089/aid.2012.0080. Epub 2012 Aug 27. AIDS Res Hum Retroviruses. 2012. PMID: 22816564 Free PMC article.
A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo.
Kenney J, Rodríguez A, Kizima L, Seidor S, Menon R, Jean-Pierre N, Pugach P, Levendosky K, Derby N, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Paglini G, Zydowsky TM, Robbiani M, Fernández Romero JA. Kenney J, et al. Among authors: zydowsky tm. Antimicrob Agents Chemother. 2013 Aug;57(8):4001-9. doi: 10.1128/AAC.00796-13. Epub 2013 Jun 10. Antimicrob Agents Chemother. 2013. PMID: 23752515 Free PMC article.
MIV-150-containing intravaginal rings protect macaque vaginal explants against SHIV-RT infection.
Ouattara LA, Barnable P, Mawson P, Seidor S, Zydowsky TM, Kizima L, Rodriguez A, Fernández-Romero JA, Cooney ML, Roberts KD, Gettie A, Blanchard J, Robbiani M, Teleshova N. Ouattara LA, et al. Among authors: zydowsky tm. Antimicrob Agents Chemother. 2014 May;58(5):2841-8. doi: 10.1128/AAC.01529-13. Epub 2014 Mar 10. Antimicrob Agents Chemother. 2014. PMID: 24614384 Free PMC article.
A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV.
Kizima L, Rodríguez A, Kenney J, Derby N, Mizenina O, Menon R, Seidor S, Zhang S, Levendosky K, Jean-Pierre N, Pugach P, Villegas G, Ford BE, Gettie A, Blanchard J, Piatak M Jr, Lifson JD, Paglini G, Teleshova N, Zydowsky TM, Robbiani M, Fernández-Romero JA. Kizima L, et al. Among authors: zydowsky tm. PLoS One. 2014 Apr 16;9(4):e94547. doi: 10.1371/journal.pone.0094547. eCollection 2014. PLoS One. 2014. PMID: 24740100 Free PMC article.
51 results