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Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis.
van der Toorn M, Slebos DJ, de Bruin HG, Leuvenink HG, Bakker SJ, Gans RO, Koëter GH, van Oosterhout AJ, Kauffman HF. van der Toorn M, et al. Among authors: de bruin hg. Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1211-8. doi: 10.1152/ajplung.00291.2006. Epub 2007 Jan 5. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17209140 Free article.
Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release.
Heijink IH, Pouwels SD, Leijendekker C, de Bruin HG, Zijlstra GJ, van der Vaart H, ten Hacken NH, van Oosterhout AJ, Nawijn MC, van der Toorn M. Heijink IH, et al. Among authors: de bruin hg. Am J Respir Cell Mol Biol. 2015 May;52(5):554-62. doi: 10.1165/rcmb.2013-0505OC. Am J Respir Cell Mol Biol. 2015. PMID: 25192219 Clinical Trial.
Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD.
Heijink IH, de Bruin HG, Dennebos R, Jonker MR, Noordhoek JA, Brandsma CA, van den Berge M, Postma DS. Heijink IH, et al. Among authors: de bruin hg. Eur Respir J. 2016 Aug;48(2):504-15. doi: 10.1183/13993003.01541-2015. Epub 2016 Apr 28. Eur Respir J. 2016. PMID: 27126693 Free article.
Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression.
Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Spira A, Lenburg ME, Guryev V, Postma DS, van den Berge M. Boudewijn IM, et al. Among authors: de bruin hg. Respir Res. 2017 Dec 21;18(1):213. doi: 10.1186/s12931-017-0696-5. Respir Res. 2017. PMID: 29268739 Free PMC article. Clinical Trial.
Cigarette smoke irreversibly modifies glutathione in airway epithelial cells.
van der Toorn M, Smit-de Vries MP, Slebos DJ, de Bruin HG, Abello N, van Oosterhout AJ, Bischoff R, Kauffman HF. van der Toorn M, et al. Among authors: de bruin hg. Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1156-62. doi: 10.1152/ajplung.00081.2007. Epub 2007 Aug 24. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17720877 Free article.
61 results