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Targeting of cancer neoantigens with donor-derived T cell receptor repertoires.
Strønen E, Toebes M, Kelderman S, van Buuren MM, Yang W, van Rooij N, Donia M, Böschen ML, Lund-Johansen F, Olweus J, Schumacher TN. Strønen E, et al. Among authors: van buuren mm, van rooij n. Science. 2016 Jun 10;352(6291):1337-41. doi: 10.1126/science.aaf2288. Epub 2016 May 19. Science. 2016. PMID: 27198675
Heterogeneous differentiation patterns of individual CD8+ T cells.
Gerlach C, Rohr JC, Perié L, van Rooij N, van Heijst JW, Velds A, Urbanus J, Naik SH, Jacobs H, Beltman JB, de Boer RJ, Schumacher TN. Gerlach C, et al. Among authors: van heijst jw, van rooij n. Science. 2013 May 3;340(6132):635-9. doi: 10.1126/science.1235487. Epub 2013 Mar 14. Science. 2013. PMID: 23493421
Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma.
van Rooij N, van Buuren MM, Philips D, Velds A, Toebes M, Heemskerk B, van Dijk LJ, Behjati S, Hilkmann H, El Atmioui D, Nieuwland M, Stratton MR, Kerkhoven RM, Kesmir C, Haanen JB, Kvistborg P, Schumacher TN. van Rooij N, et al. Among authors: van dijk lj, van buuren mm. J Clin Oncol. 2013 Nov 10;31(32):e439-42. doi: 10.1200/JCO.2012.47.7521. Epub 2013 Sep 16. J Clin Oncol. 2013. PMID: 24043743 Free PMC article. No abstract available.
Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up.
van den Berg JH, Heemskerk B, van Rooij N, Gomez-Eerland R, Michels S, van Zon M, de Boer R, Bakker NAM, Jorritsma-Smit A, van Buuren MM, Kvistborg P, Spits H, Schotte R, Mallo H, Karger M, van der Hage JA, Wouters MWJM, Pronk LM, Geukes Foppen MH, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG. van den Berg JH, et al. Among authors: van rooij n. J Immunother Cancer. 2020 Aug;8(2):e000848. doi: 10.1136/jitc-2020-000848. J Immunother Cancer. 2020. PMID: 32753545 Free PMC article. Clinical Trial.
TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.
Kvistborg P, Shu CJ, Heemskerk B, Fankhauser M, Thrue CA, Toebes M, van Rooij N, Linnemann C, van Buuren MM, Urbanus JH, Beltman JB, Thor Straten P, Li YF, Robbins PF, Besser MJ, Schachter J, Kenter GG, Dudley ME, Rosenberg SA, Haanen JB, Hadrup SR, Schumacher TN. Kvistborg P, et al. Among authors: van buuren mm, van rooij n. Oncoimmunology. 2012 Jul 1;1(4):409-418. doi: 10.4161/onci.18851. Oncoimmunology. 2012. PMID: 22754759 Free PMC article.
Manufacture of gene-modified human T-cells with a memory stem/central memory phenotype.
Gomez-Eerland R, Nuijen B, Heemskerk B, van Rooij N, van den Berg JH, Beijnen JH, Uckert W, Kvistborg P, Schumacher TN, Haanen JB, Jorritsma A. Gomez-Eerland R, et al. Among authors: van den berg jh, van rooij n. Hum Gene Ther Methods. 2014 Oct;25(5):277-87. doi: 10.1089/hgtb.2014.004. Epub 2014 Sep 22. Hum Gene Ther Methods. 2014. PMID: 25143008 Free PMC article.
Tumor organoid-T-cell coculture systems.
Cattaneo CM, Dijkstra KK, Fanchi LF, Kelderman S, Kaing S, van Rooij N, van den Brink S, Schumacher TN, Voest EE. Cattaneo CM, et al. Among authors: van den brink s, van rooij n. Nat Protoc. 2020 Jan;15(1):15-39. doi: 10.1038/s41596-019-0232-9. Epub 2019 Dec 18. Nat Protoc. 2020. PMID: 31853056 Free PMC article.
Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.
Dijkstra KK, Cattaneo CM, Weeber F, Chalabi M, van de Haar J, Fanchi LF, Slagter M, van der Velden DL, Kaing S, Kelderman S, van Rooij N, van Leerdam ME, Depla A, Smit EF, Hartemink KJ, de Groot R, Wolkers MC, Sachs N, Snaebjornsson P, Monkhorst K, Haanen J, Clevers H, Schumacher TN, Voest EE. Dijkstra KK, et al. Among authors: van leerdam me, van der velden dl, van de haar j, van rooij n. Cell. 2018 Sep 6;174(6):1586-1598.e12. doi: 10.1016/j.cell.2018.07.009. Epub 2018 Aug 9. Cell. 2018. PMID: 30100188 Free PMC article.
22 results