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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.
Kuijjer ML, Peterse EF, van den Akker BE, Briaire-de Bruijn IH, Serra M, Meza-Zepeda LA, Myklebost O, Hassan AB, Hogendoorn PC, Cleton-Jansen AM. Kuijjer ML, et al. Among authors: van den akker be. BMC Cancer. 2013 May 20;13:245. doi: 10.1186/1471-2407-13-245. BMC Cancer. 2013. PMID: 23688189 Free PMC article.
COX-2 expression in chondrosarcoma: a role for celecoxib treatment?
Schrage YM, Machado I, Meijer D, Briaire-de Bruijn I, van den Akker BE, Taminiau AH, Kalinski T, Llombart-Bosch A, Bovée JV. Schrage YM, et al. Among authors: van den akker be. Eur J Cancer. 2010 Feb;46(3):616-24. doi: 10.1016/j.ejca.2009.11.002. Epub 2009 Dec 11. Eur J Cancer. 2010. PMID: 20004565
Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.
van Oosterwijk JG, Meijer D, van Ruler MA, van den Akker BE, Oosting J, Krenács T, Picci P, Flanagan AM, Liegl-Atzwanger B, Leithner A, Athanasou N, Daugaard S, Hogendoorn PC, Bovée JV. van Oosterwijk JG, et al. Among authors: van den akker be, van ruler ma. Am J Pathol. 2013 Apr;182(4):1347-56. doi: 10.1016/j.ajpath.2012.12.036. Epub 2013 Feb 15. Am J Pathol. 2013. PMID: 23415961 Free article.
Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4.
Martins-Neves SR, Corver WE, Paiva-Oliveira DI, van den Akker BE, Briaire-de-Bruijn IH, Bovée JV, Gomes CM, Cleton-Jansen AM. Martins-Neves SR, et al. Among authors: van den akker be. J Cell Physiol. 2016 Apr;231(4):876-86. doi: 10.1002/jcp.25179. Epub 2015 Sep 9. J Cell Physiol. 2016. PMID: 26332365
Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy.
de Graaff MA, de Rooij MA, van den Akker BE, Gelderblom H, Chibon F, Coindre JM, Marino-Enriquez A, Fletcher JA, Cleton-Jansen AM, Bovée JV. de Graaff MA, et al. Among authors: van den akker be. Br J Cancer. 2016 May 24;114(11):1219-26. doi: 10.1038/bjc.2016.117. Epub 2016 May 3. Br J Cancer. 2016. PMID: 27140314 Free PMC article.
Targeting glutaminolysis in chondrosarcoma in context of the IDH1/2 mutation.
Peterse EFP, Niessen B, Addie RD, de Jong Y, Cleven AHG, Kruisselbrink AB, van den Akker BEWM, Molenaar RJ, Cleton-Jansen AM, Bovée JVMG. Peterse EFP, et al. Among authors: van den akker bewm. Br J Cancer. 2018 Apr;118(8):1074-1083. doi: 10.1038/s41416-018-0050-9. Epub 2018 Mar 26. Br J Cancer. 2018. PMID: 29576625 Free PMC article.
30 results