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Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.
Zdżalik D, Vågbø CB, Kirpekar F, Davydova E, Puścian A, Maciejewska AM, Krokan HE, Klungland A, Tudek B, van den Born E, Falnes PØ. Zdżalik D, et al. Among authors: van den born e. PLoS One. 2014 Jun 10;9(6):e98729. doi: 10.1371/journal.pone.0098729. eCollection 2014. PLoS One. 2014. PMID: 24914785 Free PMC article.
Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding.
Songe-Møller L, van den Born E, Leihne V, Vågbø CB, Kristoffersen T, Krokan HE, Kirpekar F, Falnes PØ, Klungland A. Songe-Møller L, et al. Among authors: van den born e. Mol Cell Biol. 2010 Apr;30(7):1814-27. doi: 10.1128/MCB.01602-09. Epub 2010 Feb 1. Mol Cell Biol. 2010. PMID: 20123966 Free PMC article.
Viral AlkB proteins repair RNA damage by oxidative demethylation.
van den Born E, Omelchenko MV, Bekkelund A, Leihne V, Koonin EV, Dolja VV, Falnes PØ. van den Born E, et al. Nucleic Acids Res. 2008 Oct;36(17):5451-61. doi: 10.1093/nar/gkn519. Epub 2008 Aug 21. Nucleic Acids Res. 2008. PMID: 18718927 Free PMC article.
Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins.
Zdżalik D, Domańska A, Prorok P, Kosicki K, van den Born E, Falnes PØ, Rizzo CJ, Guengerich FP, Tudek B. Zdżalik D, et al. Among authors: van den born e. DNA Repair (Amst). 2015 Jun;30:1-10. doi: 10.1016/j.dnarep.2015.02.021. Epub 2015 Mar 5. DNA Repair (Amst). 2015. PMID: 25797601 Free PMC article.
28 results