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A novel method for direct measurement of complement convertases activity in human serum.
Blom AM, Volokhina EB, Fransson V, Strömberg P, Berghard L, Viktorelius M, Mollnes TE, López-Trascasa M, van den Heuvel LP, Goodship TH, Marchbank KJ, Okroj M. Blom AM, et al. Among authors: van den heuvel lp. Clin Exp Immunol. 2014 Oct;178(1):142-53. doi: 10.1111/cei.12388. Clin Exp Immunol. 2014. PMID: 24853370 Free PMC article.
Genotype-phenotype correlations of low-frequency variants in the complement system in renal disease and age-related macular degeneration.
Geerlings MJ, Volokhina EB, de Jong EK, van de Kar N, Pauper M, Hoyng CB, van den Heuvel LP, den Hollander AI. Geerlings MJ, et al. Among authors: den hollander ai, van de kar n, van den heuvel lp. Clin Genet. 2018 Oct;94(3-4):330-338. doi: 10.1111/cge.13392. Epub 2018 Jul 10. Clin Genet. 2018. PMID: 29888403 Free PMC article.
Novel Assays to Distinguish Between Properdin-Dependent and Properdin-Independent C3 Nephritic Factors Provide Insight Into Properdin-Inhibiting Therapy.
Michels MAHM, van de Kar NCAJ, van den Bos RM, van der Velden TJAM, van Kraaij SAW, Sarlea SA, Gracchi V, Oosterveld MJS, Volokhina EB, van den Heuvel LPWJ. Michels MAHM, et al. Front Immunol. 2019 Jun 17;10:1350. doi: 10.3389/fimmu.2019.01350. eCollection 2019. Front Immunol. 2019. PMID: 31263464 Free PMC article.
Case Report: Variable Pharmacokinetic Profile of Eculizumab in an aHUS Patient.
Bouwmeester RN, Ter Avest M, Wijnsma KL, Duineveld C, Ter Heine R, Volokhina EB, Van Den Heuvel LPWJ, Wetzels JFM, van de Kar NCAJ. Bouwmeester RN, et al. Front Immunol. 2021 Jan 15;11:612706. doi: 10.3389/fimmu.2020.612706. eCollection 2020. Front Immunol. 2021. PMID: 33519821 Free PMC article.
Different Aspects of Classical Pathway Overactivation in Patients With C3 Glomerulopathy and Immune Complex-Mediated Membranoproliferative Glomerulonephritis.
Michels MAHM, van de Kar NCAJ, van Kraaij SAW, Sarlea SA, Gracchi V, Engels FAPT, Dorresteijn EM, van der Deure J, Duineveld C, Wetzels JFM, van den Heuvel LPWJ, Volokhina EB. Michels MAHM, et al. Front Immunol. 2021 Aug 11;12:715704. doi: 10.3389/fimmu.2021.715704. eCollection 2021. Front Immunol. 2021. PMID: 34456924 Free PMC article.
Long-term follow-up including extensive complement analysis of a pediatric C3 glomerulopathy cohort.
Michels MAHM, Wijnsma KL, Kurvers RAJ, Westra D, Schreuder MF, van Wijk JAE, Bouts AHM, Gracchi V, Engels FAPT, Keijzer-Veen MG, Dorresteijn EM, Volokhina EB, van den Heuvel LPWJ, van de Kar NCAJ. Michels MAHM, et al. Pediatr Nephrol. 2022 Mar;37(3):601-612. doi: 10.1007/s00467-021-05221-6. Epub 2021 Sep 2. Pediatr Nephrol. 2022. PMID: 34476601 Free PMC article.
389 results