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Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway.
Brum AM, van de Peppel J, van der Leije CS, Schreuders-Koedam M, Eijken M, van der Eerden BC, van Leeuwen JP. Brum AM, et al. Among authors: van der leije cs, van de peppel j, van leeuwen jp, van der eerden bc. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12711-6. doi: 10.1073/pnas.1501597112. Epub 2015 Sep 29. Proc Natl Acad Sci U S A. 2015. PMID: 26420877 Free PMC article.
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5.
Hoenderop JG, van Leeuwen JP, van der Eerden BC, Kersten FF, van der Kemp AW, Mérillat AM, Waarsing JH, Rossier BC, Vallon V, Hummler E, Bindels RJ. Hoenderop JG, et al. Among authors: van leeuwen jp, van der kemp aw, van der eerden bc. J Clin Invest. 2003 Dec;112(12):1906-14. doi: 10.1172/JCI19826. J Clin Invest. 2003. PMID: 14679186 Free PMC article.
Hypervitaminosis D mediates compensatory Ca2+ hyperabsorption in TRPV5 knockout mice.
Renkema KY, Nijenhuis T, van der Eerden BC, van der Kemp AW, Weinans H, van Leeuwen JP, Bindels RJ, Hoenderop JG. Renkema KY, et al. Among authors: van leeuwen jp, van der kemp aw, van der eerden bc. J Am Soc Nephrol. 2005 Nov;16(11):3188-95. doi: 10.1681/ASN.2005060632. Epub 2005 Sep 7. J Am Soc Nephrol. 2005. PMID: 16148038
The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption.
van der Eerden BC, Hoenderop JG, de Vries TJ, Schoenmaker T, Buurman CJ, Uitterlinden AG, Pols HA, Bindels RJ, van Leeuwen JP. van der Eerden BC, et al. Among authors: van leeuwen jp. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17507-12. doi: 10.1073/pnas.0505789102. Epub 2005 Nov 16. Proc Natl Acad Sci U S A. 2005. PMID: 16291808 Free PMC article.
Klotho prevents renal calcium loss.
Alexander RT, Woudenberg-Vrenken TE, Buurman J, Dijkman H, van der Eerden BC, van Leeuwen JP, Bindels RJ, Hoenderop JG. Alexander RT, et al. Among authors: van leeuwen jp, van der eerden bc. J Am Soc Nephrol. 2009 Nov;20(11):2371-9. doi: 10.1681/ASN.2008121273. Epub 2009 Aug 27. J Am Soc Nephrol. 2009. PMID: 19713312 Free PMC article.
The T-13910C polymorphism in the lactase phlorizin hydrolase gene is associated with differences in serum calcium levels and calcium intake.
Koek WN, van Meurs JB, van der Eerden BC, Rivadeneira F, Zillikens MC, Hofman A, Obermayer-Pietsch B, Lips P, Pols HA, Uitterlinden AG, van Leeuwen JP. Koek WN, et al. Among authors: van leeuwen jp, van meurs jb, van der eerden bc. J Bone Miner Res. 2010 Sep;25(9):1980-7. doi: 10.1002/jbmr.83. J Bone Miner Res. 2010. PMID: 20225268 Free article.
Basic techniques in human mesenchymal stem cell cultures: differentiation into osteogenic and adipogenic lineages, genetic perturbations, and phenotypic analyses.
Bruedigam C, Driel Mv, Koedam M, Peppel Jv, van der Eerden BC, Eijken M, van Leeuwen JP. Bruedigam C, et al. Among authors: van leeuwen jp, van der eerden bc. Curr Protoc Stem Cell Biol. 2011 Jun;Chapter 1:Unit1H.3. doi: 10.1002/9780470151808.sc01h03s17. Curr Protoc Stem Cell Biol. 2011. PMID: 21633940
The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice.
van der Eerden BC, Weissgerber P, Fratzl-Zelman N, Olausson J, Hoenderop JG, Schreuders-Koedam M, Eijken M, Roschger P, de Vries TJ, Chiba H, Klaushofer K, Flockerzi V, Bindels RJ, Freichel M, van Leeuwen JP. van der Eerden BC, et al. Among authors: van leeuwen jp. J Cell Physiol. 2012 May;227(5):1951-9. doi: 10.1002/jcp.22923. J Cell Physiol. 2012. PMID: 21732366
120 results