Self-limited adverse reaction to human-derived collagen injectable product

Dermatol Surg. 2000 Oct;26(10):936-8. doi: 10.1046/j.1524-4725.2000.026010936.x.

Abstract

Background: Soft tissue augmentation is a common and safe cosmetic and reconstructive procedure.

Objective: We describe a temporary and self-limited adverse reaction to Dermalogen.

Methods: Clinical and histologic evaluation following an adverse reaction noted at a Dermalogen skin test site.

Results: Our patient was found to have a foreign body reaction to Dermalogen.

Conclusion: Dermalogen, a form of acellular human collagen, may induce a foreign body reaction.

Publication types

  • Case Reports

MeSH terms

  • Biocompatible Materials / administration & dosage
  • Biocompatible Materials / adverse effects*
  • Collagen / administration & dosage
  • Collagen / adverse effects*
  • Female
  • Foreign-Body Reaction / etiology*
  • Foreign-Body Reaction / physiopathology
  • Humans
  • Injections, Subcutaneous
  • Middle Aged
  • Remission, Spontaneous
  • Rhytidoplasty / methods
  • Skin Tests
  • Skin* / drug effects
  • Skin* / pathology

Substances

  • Biocompatible Materials
  • Collagen