Tamoxifen retinopathy in a male patient

Am J Ophthalmol. 2001 Mar;131(3):386-7. doi: 10.1016/s0002-9394(00)00781-9.

Abstract

Purpose: To report a case of tamoxifen retinopathy in a male patient.

Methods: Case report. A 68-year-old man, who had received a cumulative tamoxifen dose of 60 g over 33 months for unresectable hepatocellular carcinoma, was evaluated.

Results: A peculiar, bilateral, symmetric, inner retinal crystalline deposition associated with mild macular edema was discovered. No other ocular toxicity of tamoxifen was observed.

Conclusion: To our knowledge, this is the first report of tamoxifen retinopathy in a male.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Agents, Hormonal / adverse effects*
  • Carcinoma, Hepatocellular / drug therapy
  • Humans
  • Liver Neoplasms / drug therapy
  • Male
  • Retina / drug effects*
  • Retinal Diseases / chemically induced*
  • Retinal Diseases / pathology
  • Tamoxifen / adverse effects*
  • Visual Acuity

Substances

  • Antineoplastic Agents, Hormonal
  • Tamoxifen