Combined phototherapeutic keratectomy and therapeutic contact lens for recurrent erosions in bullous keratopathy

Br J Ophthalmol. 2001 Aug;85(8):908-11. doi: 10.1136/bjo.85.8.908.

Abstract

Aims: To evaluate the therapeutic effects of excimer laser phototherapeutic keratectomy (PTK) combined with therapeutic contact lens for painful recurrent corneal erosions (RCE) secondary to bullous keratopathy (BK) not suitable for penetrating keratoplasty.

Methods: Excimer laser PTK was performed prospectively in eight eyes with painful RCE due to BK visually expecting no benefit from penetrating keratoplasty. After mechanical removal of the epithelium, the corneas were ablated with 50 pulses in the central 6.5 mm zone (ablation rate 0.25 microm per pulse) and another 200 pulses for polishing the periphery. After PTK, therapeutic contact lenses were applied for 3 months. The mean follow up period after PTK was 10.9 months (ranging from 6 to 15 months).

Results: All patients experienced relief of their pain symptoms after the epithelium healed. Only one patient complained of occasional stinging pain with intermittent recurrence of small bullae. He refused a second treatment because the pain was much less than that before the surgery and quite tolerable. No infection or other complications were noted.

Conclusion: PTK with deeper ablation and adjunctive therapeutic contact lens is an easy to perform and effective treatment with less recurrence rate for patients with BK and poor visual potential.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Combined Modality Therapy
  • Contact Lenses, Extended-Wear*
  • Corneal Ulcer / etiology
  • Corneal Ulcer / therapy*
  • Female
  • Humans
  • Lasers, Excimer
  • Male
  • Middle Aged
  • Pain / etiology
  • Pain Management
  • Photorefractive Keratectomy / methods*
  • Treatment Outcome