On a group of 18 eyes the authors evaluate their experience with medicamentous and laser therapy of central serous chorioretinopathy. They report unsatisfactory results in the group of patients treated with non-steroid antiphlogistics, resorbents, vasoprotective agents, vitamins, where they observed adherence of ablated neuroepithelium in 4 eyes on average after 5.5 weeks. But in 7 similarly treated eyes adherence of the ablation did not occur even after 4 months. The authors confirm the value of direct laser photocoagulation for reducing the period of ablation in central serous chorioretinopathy. In all 11 photocoagulations of treated eyes the ablation adhered on average after 5.2 weeks. The authors maintain that they achieved better final visual acuity and greater improvement of visual acuity in patients where the ablation period of the neuroepithelium was shorter than in patients with a prolonged course of ablation.