Bacillary angiomatosis of the anterior orbit, eyelid, and conjunctiva

Am J Ophthalmol. 2002 Sep;134(3):433-4. doi: 10.1016/s0002-9394(02)01530-1.

Abstract

Purpose: To report a case of bacillary angiomatosis of the lower eyelid, conjunctiva, and anterior orbit.

Design: Interventional case report.

Methods: A 76-year-old immunocompromised male patient developed a firm vascularized nodule in his left lower eyelid and anterior orbit.

Results: An excisional biopsy was performed. Histopathologic examination revealed an abnormal vascular proliferation and a mixed inflammatory infiltrate. A Warthin-Starry stain showed numerous bacilli. These findings are characteristic of bacillary angiomatosis. A serologic specimen was positive for antibodies to Bartonella Quintana.

Conclusion: The lower lid and anterior orbit are rare locations for bacillary angiomatosis. Our case brings to attention the increasing importance of Bartonella infection as a causative agent of ophthalmic diseases.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiomatosis, Bacillary / drug therapy
  • Angiomatosis, Bacillary / microbiology*
  • Angiomatosis, Bacillary / pathology
  • Anti-Bacterial Agents / therapeutic use
  • Bartonella quintana / isolation & purification*
  • Conjunctival Diseases / drug therapy
  • Conjunctival Diseases / microbiology*
  • Conjunctival Diseases / pathology
  • Doxycycline / therapeutic use
  • Drug Therapy, Combination / therapeutic use
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / microbiology*
  • Eye Infections, Bacterial / pathology
  • Eyelid Diseases / drug therapy
  • Eyelid Diseases / microbiology*
  • Eyelid Diseases / pathology
  • Humans
  • Immunocompromised Host
  • Male
  • Orbital Diseases / drug therapy
  • Orbital Diseases / microbiology*
  • Orbital Diseases / pathology
  • Rifampin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Doxycycline
  • Rifampin