Adult wilms' tumor metastatic to the choroid of the eye

Ophthalmology. 2002 Nov;109(11):2134-6. doi: 10.1016/s0161-6420(02)01280-0.

Abstract

Background: Ocular manifestations of Wilms' tumor are rare, particularly in adults. We present the first reported case of a choroidal metastasis resulting from Wilms' tumor.

Design: Case report.

Participant: A 37-year-old white male with an adult-onset biopsy-proven Wilms' tumor with multiorgan metastatic disease.

Results: We report a unique case of uveal metastasis presumed from a Wilms' tumor. The patient's history included a primary Wilms' tumor with known disseminated metastasis, orbital pain, metamorphopsia, and decreased vision. Ophthalmoscopy revealed a unifocal choroidal tumor in the inferotemporal quadrant of the right eye. Ultrasonographic measurements of the tumor were 4.9 mm in apical height and 15 x 13 mm in basal diameter. Unusual ultrasound findings included echodense stromal opacities and retrobulbar edema. Fluorescein angiography revealed double circulation and late intratumoral fluorescence.

Conclusions: This is the first reported case of a choroidal metastasis by a Wilms' tumor.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Choroid Neoplasms / diagnostic imaging
  • Choroid Neoplasms / secondary*
  • Fatal Outcome
  • Fluorescein Angiography
  • Humans
  • Kidney Neoplasms / pathology*
  • Male
  • Ultrasonography
  • Wilms Tumor / diagnostic imaging
  • Wilms Tumor / secondary*