Background: Visual abnormalities have been described in patients with infantile spasms (IS), an epileptic syndrome of early childhood.
Methods: We report on 3 children who exhibited cortically mediated visual regression in association with the development of IS.
Results: In 1 patient, loss of visual behavior was the presenting complaint. In all patients, visual behavior improved with treatment of seizures.
Conclusions: IS are a potentially treatable cause of cortically impaired vision in early childhood. Because visual behavior might improve when the seizures are treated, patients should be referred appropriately.