Ehrlichiosis optic neuritis

Am J Ophthalmol. 2003 Mar;135(3):412-3. doi: 10.1016/s0002-9394(02)01945-1.

Abstract

Purpose: To describe a case of ehrlichiosis optic neuritis.

Design: Single observational case report.

Methods: A 41-year-old woman with symptoms and clinical and imaging signs consistent with optic neuritis presented to a tertiary care academic center for comprehensive neuro-ophthalmic evaluation. Main outcome measures included preoptic and postoptic neuritis polyvalent ehrlichiosis titers and magnetic resonance imaging (MRI) of orbits with gadolinium.

Results: Ehrlichiosis titers drawn 11 days before onset of eye symptoms were negative. Titers drawn 7 days after symptoms began were positive. The optic nerve enhanced with gadolinium on MRI.

Conclusions: Ehrlichiosis can cause optic neuritis and should be considered in patients with optic neuritis after a febrile, flu-like illness in an endemic area.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Antibodies, Bacterial / blood
  • Doxycycline / therapeutic use
  • Ehrlichia / immunology
  • Ehrlichiosis / complications*
  • Ehrlichiosis / diagnosis
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / etiology*
  • Female
  • Humans
  • Lymphocytes / microbiology
  • Magnetic Resonance Imaging
  • Optic Neuritis / diagnosis
  • Optic Neuritis / drug therapy
  • Optic Neuritis / etiology*

Substances

  • Anti-Bacterial Agents
  • Antibodies, Bacterial
  • Doxycycline