Trans-Tenon's retrobulbar triamcinolone infusion for the treatment of uveitis

Br J Ophthalmol. 2003 Aug;87(8):968-71. doi: 10.1136/bjo.87.8.968.

Abstract

Aim: To assess efficacy and complications of trans-Tenon's retrobulbar infusion of triamcinolone acetonide for posterior uveitic inflammation.

Methods: Non-randomised, uncontrolled, retrospective study of 51 eyes of 37 patients who underwent triamcinolone infusion for vitritis, cystoid macular oedema (CMO), or posterior retinal vasculitis using a long blunt cannula via an incision made through conjunctiva and Tenon's capsule.

Results: Overall clinical efficacy was 86%; 96% for vitritis, 82% for CMO, and 33% for posterior retinal vasculitis. Mean visual acuity improved within 1 month after triamcinolone infusion (p <0.05). Cataract progression and intraocular pressure elevation were observed in 31% and 27% of eyes, respectively.

Conclusion: Trans-Tenon's retrobulbar triamcinolone infusion may be a safe and effective treatment for posterior uveitic inflammation.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Inflammatory Agents / administration & dosage*
  • Cataract / pathology
  • Disease Progression
  • Female
  • Glucocorticoids / administration & dosage*
  • Humans
  • Infusions, Intralesional
  • Intraocular Pressure / drug effects
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome
  • Triamcinolone Acetonide / administration & dosage*
  • Uveitis, Posterior / drug therapy*
  • Uveitis, Posterior / physiopathology
  • Visual Acuity / drug effects

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Triamcinolone Acetonide