Purpose: To evaluate the success of treatment and prevention of recurrence of Salzmann's nodules by superficial keratectomy with intraoperative mitomycin-C (MMC).
Setting: Price Vision Group, Indianapolis, Indiana, USA.
Methods: This retrospective consecutive case series comprised 30 eyes of 25 patients who had superficial keratectomy with MMC between January 1997 and June 2000 at a large tertiary-care center.
Results: Twenty-four patients reported improvement in their symptoms. The remaining patient lost 1 line of visual acuity. Ninety-seven percent of eyes maintained or improved best corrected visual acuity. No patient had a recurrence of Salzmann's nodular degeneration over a mean follow-up of 28 months +/- 15 (SD) (range 4.0 days to 4.1 years).
Conclusion: Superficial keratectomy with MMC appears to be a valid and safe method for treating and preventing the recurrence of Salzmann's nodular degeneration.