Large hemorrhagic retinal pigment epithelial detachments (RPEDs) with presumed subretinal neovascularization (SRN) generally have a poor visual prognosis. We report the case of a 70-year-old woman who initially had a large serous hemorrhagic RPED associated with lipid exudation and juxtafoveal SRN. Without treatment, spontaneous resolution occurred with subsequent visual improvement.