Bilateral serous macular detachment as a presenting feature of acute lymphoblastic leukemia

Eur J Ophthalmol. 2005 Mar-Apr;15(2):284-6. doi: 10.1177/112067210501500219.

Abstract

Purpose: To report a case of bilateral serous maculopathy as an initial sign of acute lymphoblastic leukaemia in children.

Methods/results: A 13-year-old girl, who presented with symptoms of visual blurring, was found to have a bilateral serous maculopathy. Haematological abnormalities (thrombocytopenia with a mild lymphocytosis) prompted further investigation. A bone marrow aspirate revealed the presence of leukemic blasts and a diagnosis of acute lymphoblastic leukaemia was made. Her maculopathy completely resolved following systemic chemotherapy.

Conclusions: Prompt recognition of disease led to early systemic treatment and restoration of visual function.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Diagnosis, Differential
  • Female
  • Fluorescein Angiography
  • Humans
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Retinal Detachment / diagnosis*
  • Vision Disorders / diagnosis