Vogt-Koyanagi-Harada associated with diabetes mellitus and celiac disease in a 3-year-old girl

Eur J Ophthalmol. 2006 Jan-Feb;16(1):173-7. doi: 10.1177/112067210601600130.

Abstract

Purpose: To present a case of Vogt-Koyanagi-Harada (VKH) associated with type I diabetes mellitus and celiac disease in a 3 year old female.

Methods: We studied a three-year old female who presented with clinical manifestation of VKH and type I Diabetes mellitus and celiac disease.

Results: Patient was found to have hyperglycemia with type I diabetes mellitus. Duodenal mucosal biopsy specimen confirmed the diagnosis of celiac disease. Patient's ocular inflammation was treated by topical and systemic corticosteroid and immune-suppressive therapy. Her diabetes mellitus was controlled by insulin and her celiac disease was controlled by gluten-free diet.

Conclusions: The association of VKH with two autoimmune diseases (celiac disease and type I diabetes mellitus) is rare. This case is, to our knowledge, the youngest patient reported with VKH.

Publication types

  • Case Reports

MeSH terms

  • Celiac Disease / complications*
  • Celiac Disease / diet therapy
  • Child, Preschool
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 1 / drug therapy
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Hyperglycemia / diagnosis
  • Immunosuppressive Agents / therapeutic use
  • Insulin / therapeutic use
  • Uveomeningoencephalitic Syndrome / drug therapy
  • Uveomeningoencephalitic Syndrome / etiology*

Substances

  • Glucocorticoids
  • Immunosuppressive Agents
  • Insulin