[Seroprevalence of IgG antibodies against parvovirus B19 among blood donors from Santiago, Chile]

Rev Med Chil. 2007 Apr;135(4):443-8. doi: 10.4067/s0034-98872007000400005. Epub 2007 May 16.
[Article in Spanish]

Abstract

Background: Parvovirus B19 (B19) is associated with a wide range of disease manifestations, whose severity depends on the immunological and hematological status of the host. Infection with B19 has been reported worldwide and the prevalence of immunoglobulin G antibodies against B19 increases with age and varies by location and time of the last B19 epidemic.

Aim: To evaluate the prevalence of IgG antibodies against Parvavirus B19 virus in a population of volunteer blood donors at two hospital blood banks in Santiago, Chile.

Material and methods: A total of 400 serum samples from blood donors aged 18 to 65 years, were examined for the presence of IgG antibodies against Parvovirus B19.

Results: The overall prevalence of IgG antibodies was 54.8%. No significant difference was found between men and women (57.6% and 49.3%, respectively).

Conclusions: IgG antibody seroprevalence against Parvovirus B19, was 55% in this sample of Chilean blood donors. This figure is in agreement with previous reports from abroad.

Publication types

  • English Abstract
  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Age Factors
  • Aged
  • Antibodies, Viral / blood*
  • Blood Donors*
  • Chile
  • Female
  • Humans
  • Immunoglobulin G / blood*
  • Male
  • Middle Aged
  • Parvovirus B19, Human / immunology*
  • Reproducibility of Results
  • Seroepidemiologic Studies
  • Sex Distribution

Substances

  • Antibodies, Viral
  • Immunoglobulin G