Background: Various modalities have been available to treat primary cutaneous malignancies. Although not indicated for certain aggressive tumors, many of the newest regimens involve noninvasive techniques. It behooves both the nonsurgeon and the surgeon alike to be apprised of all treatment options, their indications, and their efficacy.
Objective: The objective was to review the indications and published data on various nonsurgical treatment options for primary cutaneous malignancy.
Methods and materials: This study is a literature review.
Conclusions: Many nonsurgical treatment options exist for primary cutaneous malignancies. In determining which modalities to implement, consideration must be given to careful patient selection, tumor type, and appropriate expectations. Additionally, adjunctive/combination therapy may be used before or after surgery.