Comparison of surgical procedures for vitreous surgery in diabetic macular edema

Jpn J Ophthalmol. 2009 Mar;53(2):120-124. doi: 10.1007/s10384-008-0639-2. Epub 2009 Mar 31.

Abstract

Purpose: Results of vitreous surgery alone in patients with diabetic macular edema (Vit group) were compared with results of surgery combined with peeling of the internal limiting membrane (ILM group), and surgery combined with removal of the residual vitreous cortex after its visualization using triamcinolone acetonide (TA) and a postoperative intravitreal TA injection (TA group). Visual acuities after the operation, degree of improvement in visual acuity (VA), and intra- and postoperative complications were evaluated.

Methods: The study included 141 consecutive patients (168 eyes) who could be followed up for at least 12 months after the operation. The Vit group consisted of 66 eyes, the ILM group of 62 eyes, and the TA group of 40 eyes. Patient background factors, and visual acuities 6 and 12 months after operation were evaluated first, and at the final examination, the degree of improvement in VA, the incidences of intra- and postoperative complications, and the incidence of intraocular pressure > or =25 mmHg were studied.

Results: Preoperative VA was compared with the 6- and 12-month postoperative VA and the VA at the final examination. The preoperative to 6 months postoperative improvements and those between the 12-month postoperative and final examination did not differ among the three groups. However, the degree of improvement in VA between 6 and 12 months after the operation was significantly smaller in the TA group than in the other two groups. The incidences of intra- and postoperative complications did not differ among the three groups, but the incidence of intraocular pressure >/=25 mmHg was slightly higher in the TA group.

Conclusion: Surgical results did not differ among the three operative techniques examined in this study.

Publication types

  • Comparative Study

MeSH terms

  • Basement Membrane / surgery
  • Diabetic Retinopathy / surgery*
  • Female
  • Humans
  • Intraocular Pressure
  • Intraoperative Complications
  • Macular Edema / surgery*
  • Male
  • Middle Aged
  • Postoperative Complications
  • Triamcinolone Acetonide / administration & dosage
  • Visual Acuity / physiology
  • Vitrectomy / methods*
  • Vitreous Body / pathology
  • Vitreous Body / surgery*

Substances

  • Triamcinolone Acetonide