Minimally invasive dorsal percutaneous spondylodesis for the treatment of adult pyogenic spondylodiscitis

Acta Neurochir (Wien). 2009 Nov;151(11):1451-7. doi: 10.1007/s00701-009-0377-3. Epub 2009 May 26.

Abstract

Background: Most adult patients with pyogenic lumbar or thoracic spondylodiscitis are treated with an external orthosis and antimicrobial therapy for several weeks to months. If surgical intervention is required, a combined anterior and posterior approach for debridement and fusion with autologous bone graft or titanium mesh cage is usually performed.

Method: We here report on our experience with the use of a minimally invasive percutaneous dorsal pedicle screw-rod spondylodesis in adult patients with pyogenic lumbar or thoracic spondylodiscitis.

Findings: Eight patients with lumbar, one with thoracolumbar and three with thoracic pyogenic spondylodiscitis with a mean back pain of 9/10 on the visual analog scale (VAS) and without corresponding neurological deficits were treated. Immediately after the operation, we calculated a significant reduction of the back pain on the VAS to 1.7, of leukocyte counts and C-reactive protein levels. After a mean of 61 days of continuous antimicrobial therapy during full mobilization, all patients were pain free, and leukocyte counts as well as C-reactive protein levels were normalized.

Conclusions: We conclude that minimally invasive percutaneous fixation is a feasible and effective technique to achieve immediate pain release, avoid long-term immobilization and overcome the disadvantages of a dorsoventral procedure. However, surgical complications and possible follow-up procedures supplement the patients' risks of adverse reactions of the disease.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Bed Rest / adverse effects
  • Bone Screws
  • Discitis / drug therapy
  • Discitis / microbiology
  • Discitis / surgery*
  • Female
  • Humans
  • Immobilization / adverse effects
  • Internal Fixators
  • Low Back Pain / drug therapy
  • Low Back Pain / microbiology
  • Low Back Pain / surgery*
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / pathology
  • Lumbar Vertebrae / surgery
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures / instrumentation
  • Minimally Invasive Surgical Procedures / methods*
  • Osteomyelitis / diagnosis
  • Osteomyelitis / drug therapy
  • Osteomyelitis / surgery*
  • Pain Measurement
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control
  • Spinal Fusion / instrumentation
  • Spinal Fusion / methods*
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / pathology
  • Thoracic Vertebrae / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents