'Primary cutaneous mucormycosis during induction chemotherapy in a child with acute lymphoblastic leukemia'

Indian J Pediatr. 2009 Nov;76(11):1161-3. doi: 10.1007/s12098-009-0280-1. Epub 2010 Jan 14.

Abstract

We report a child with acute lymphoblastic leukemia who developed primary cutaneous mucormycosis at the site of lumbar puncture during induction chemotherapy. Though high mortality rates are reported with invasive mucormycosis, prompt biopsy, early identification and antifungal therapy using a combination regime of amphotericin-B and rifampicin along with extensive surgical debridement led to complete cure of the lesions in the index case.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / therapeutic use
  • Child, Preschool
  • Humans
  • Male
  • Mucormycosis / chemically induced*
  • Mucormycosis / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Skin Diseases / chemically induced*
  • Skin Diseases / drug therapy

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents
  • Amphotericin B