Abstract
Prolactin-secreting pituitary tumors are a common cause of amenorrhea and infertility in premenopausal women. The goals of therapy are to normalize prolactin, restore gonadal function and fertility, and reduce tumor size, and dopamine agonists are the preferred therapy. Clinically significant tumor enlargement during pregnancy is uncommon and dependent on tumor size and prepregnancy treatment.
Copyright © 2011 Elsevier Inc. All rights reserved.
MeSH terms
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Dopamine Agonists / adverse effects
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Dopamine Agonists / therapeutic use
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Female
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Fetal Development / drug effects
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Humans
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Hyperprolactinemia / complications*
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Hyperprolactinemia / physiopathology
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Hyperprolactinemia / therapy
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Infertility, Female / etiology*
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Pituitary Neoplasms / pathology
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Pituitary Neoplasms / physiopathology
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Pituitary Neoplasms / therapy
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Pregnancy
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Pregnancy Complications
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Pregnancy Complications, Neoplastic
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Prolactinoma / pathology
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Prolactinoma / physiopathology
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Prolactinoma / therapy