Comparison of central corneal thickness measurements by Galilei Dual-Scheimpflug analyzer® and ultrasound pachymeter in myopic eyes

Ophthalmic Surg Lasers Imaging. 2012 Mar-Apr;43(2):128-34. doi: 10.3928/15428877-20120102-08. Epub 2012 Feb 9.

Abstract

Background and objective: To compare the central corneal thickness (CCT) measurements by Galilei Dual-Scheimpflug analyzer (GSA) (Ziemer Group, Port, Switzerland) and ultrasound pachymeter (UP) in myopic eyes.

Patients and methods: In this prospective study, CCT of 161 myopic eyes of 81 refractive surgery candidates (35 female, 46 male; mean age: 23.18 ± 4.08 years) were measured by GSA and UP consecutively. The data were analyzed statistically by paired t test, Bland-Altman plot, and Pearson correlation test to assess the agreement of the measurements.

Results: The mean CCTs obtained by GSA and UP were 559.85 ± 30.87 and 560.41 ± 34.45 μm, respectively. No significant difference was found between the measurements (P = .684) and regression analysis showed a high correlation between the measurements obtained with both devices (r = 0.86; P < .001). A strong agreement between the two methods was also found by Bland-Altman plot.

Conclusion: In myopic eyes, the CCT measurements of GSA and UP are similar and highly correlated. Because of high agreement between these devices, the GSA is a non-contact method that may be an alternative to UP for measurement of CCT.

MeSH terms

  • Adolescent
  • Adult
  • Cornea / diagnostic imaging
  • Cornea / pathology*
  • Diagnostic Techniques, Ophthalmological / instrumentation*
  • Female
  • Humans
  • Male
  • Myopia / diagnostic imaging
  • Myopia / pathology*
  • Photography / methods
  • Prospective Studies
  • Regression Analysis
  • Ultrasonography / instrumentation
  • Young Adult