Idiopathic isolated orbicularis weakness

Eye (Lond). 2012 May;26(5):746-8. doi: 10.1038/eye.2012.5. Epub 2012 Feb 10.

Abstract

Purpose: Orbicularis weakness is commonly associated with seventh nerve palsy or neuromuscular and myopathic conditions such as myotonic dystrophy and myasethenia gravis. We report four cases of idiopathic isolated orbicularis weakness.

Methods: All four cases were female and the presenting symptoms of ocular irritation and epiphora had been present for over 7 years in three patients. All patients had lagophthalmos and three had ectropion. Three patients underwent full investigations which excluded known causes of orbicularis weakness. Two patients underwent oribularis oculi muscle biopsy and histological confirmation of orbicularis atrophy.

Results: All patients underwent surgery to specifically address the orbicularis weakness with satisfactory outcomes and alleviation of symptoms in all cases. Isolated orbicularis weakness may be a relatively common entity that is frequently overlooked.

Conclusion: Early recognition of this condition may lead to better management and prevent patients undergoing unnecessary surgical procedures.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Atrophy
  • Biopsy
  • Eyelid Diseases / diagnosis*
  • Eyelid Diseases / surgery
  • Female
  • Humans
  • Muscle Weakness / diagnosis*
  • Muscle Weakness / surgery
  • Oculomotor Muscles / pathology*
  • Ophthalmologic Surgical Procedures