Breast milk parasite-specific antibodies and protection from amebiasis and cryptosporidiosis in Bangladeshi infants: a prospective cohort study

Clin Infect Dis. 2013 Apr;56(7):988-92. doi: 10.1093/cid/cis1044. Epub 2012 Dec 12.

Abstract

In this prospective cohort study, the presence of parasite-specific immunoglobulin A in breast milk was associated with protection of Bangladeshi infants from cryptosporidiosis and amebiasis. Our findings suggest that passive immunity could be harnessed for the prevention of Entamoeba histolytica and Cryptosporidium species infection in children living in endemic regions.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Protozoan / analysis*
  • Bangladesh
  • Cohort Studies
  • Cryptosporidiosis / prevention & control*
  • Cryptosporidium / immunology
  • Entamoeba histolytica / immunology
  • Entamoebiasis / prevention & control*
  • Female
  • Humans
  • Immunity, Maternally-Acquired
  • Immunoglobulin G / analysis*
  • Infant
  • Infant, Newborn
  • Male
  • Milk, Human / immunology*
  • Pregnancy
  • Prospective Studies

Substances

  • Antibodies, Protozoan
  • Immunoglobulin G