Clinical characteristics of intermediate uveitis in Chinese patients

Ocul Immunol Inflamm. 2013;21(1):71-6. doi: 10.3109/09273948.2012.736587.

Abstract

Purpose: To describe the clinical characteristics of Chinese patients with intermediate uveitis (IU).

Methods: Retrospective review of patients with IU with at least 6 months follow-up.

Results: Seventy patients were identified and the mean follow-up was 59.7 months. The mean age at presentation was 33.1 years. Fifteen (21.4%) patients had disease onset before the age of 18 years; 91.4% of IU cases were considered idiopathic after investigations. At the last follow-up, 85 (74.6%) eyes retained vision of at least 20/40. Poor visual outcome was significantly associated with poor presenting visual acuity (p = .002), presence of epiretinal membrane or atrophic macular changes (p = .003), persistent cystoid macular edema (p = .015), and increased disease duration (odds ratio = 1.015 per month, p = .002). Pediatric patients were more likely to have bilateral (p = .003) and chronic disease (p < .001).

Conclusions: IU in Chinese patients was mainly idiopathic, with good visual outcomes in most patients after appropriate treatment.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Female
  • Fluorescein Angiography
  • Follow-Up Studies
  • Fundus Oculi
  • Glucocorticoids / administration & dosage*
  • Hong Kong / epidemiology
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Incidence
  • Intravitreal Injections
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • Time Factors
  • Uveitis, Intermediate / diagnosis
  • Uveitis, Intermediate / drug therapy
  • Uveitis, Intermediate / epidemiology*
  • Young Adult

Substances

  • Glucocorticoids
  • Immunosuppressive Agents