Abstract
Solitary fibrous tumor (SFT) is a rare soft-tissue neoplasm which may occur at any site although it is more frequent in the pleura, mediastinum and lung. Orbital involvement by SFT is uncommon. Giant cells are extremely rare to be seen in a SFT and have been described to be immunoreactive for CD34. We present a case of orbital SFT with multinucleate giant cells expressing CD68 and lacking immunoreactivity for CD34. The differential diagnosis is discussed.
MeSH terms
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Adult
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Antigens, CD / analysis
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Antigens, CD34 / analysis
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Antigens, Differentiation, Myelomonocytic / analysis
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Female
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Giant Cells / chemistry
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Giant Cells / cytology*
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Head / diagnostic imaging
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Histocytochemistry
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Humans
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Immunohistochemistry
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Microscopy
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Orbital Neoplasms / diagnosis*
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Orbital Neoplasms / pathology*
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Solitary Fibrous Tumors / diagnosis*
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Solitary Fibrous Tumors / pathology*
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Tomography, X-Ray Computed
Substances
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Antigens, CD
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Antigens, CD34
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Antigens, Differentiation, Myelomonocytic
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CD68 antigen, human