Fatal fulminant hepatitis E associated with autoimmune hepatitis and excessive paracetamol intake in Southeastern France

J Clin Microbiol. 2014 Apr;52(4):1294-7. doi: 10.1128/JCM.03372-13. Epub 2014 Jan 29.

Abstract

We present, to our knowledge, the first case of fatal fulminant liver failure associated with hepatitis E virus infection, autoimmune hepatitis, and excessive paracetamol intake, which occurred in a 77-year-old woman. Hepatitis E testing should be performed in severe acute liver failure cases, even when another cause has been identified.

Publication types

  • Case Reports

MeSH terms

  • Acetaminophen / administration & dosage*
  • Acetaminophen / adverse effects
  • Aged
  • Analgesics, Non-Narcotic / administration & dosage*
  • Analgesics, Non-Narcotic / adverse effects
  • Cluster Analysis
  • Fatal Outcome
  • Female
  • France
  • Hepatitis E / complications
  • Hepatitis E / diagnosis*
  • Hepatitis E / pathology
  • Hepatitis E virus / genetics
  • Hepatitis E virus / isolation & purification*
  • Hepatitis, Autoimmune / complications
  • Hepatitis, Autoimmune / diagnosis*
  • Hepatitis, Autoimmune / pathology
  • Humans
  • Liver Failure / diagnosis*
  • Liver Failure / etiology
  • Liver Failure / pathology
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Viral / genetics
  • Sequence Analysis, DNA

Substances

  • Analgesics, Non-Narcotic
  • RNA, Viral
  • Acetaminophen

Associated data

  • GENBANK/KF921517
  • GENBANK/KF921518