Ophthalmic use of blood-derived products

Surv Ophthalmol. 2015 Sep-Oct;60(5):406-34. doi: 10.1016/j.survophthal.2015.03.003. Epub 2015 Apr 15.

Abstract

There is a wide spectrum of blood-derived products that have been used in many different medical and surgical specialties with success. Blood-derived products for clinical use can be extracted from autologous or allogeneic specimens of blood, but recombinant products are also commonly used. A number of blood derivatives have been used for a wide range of ocular conditions, from the ocular surface to the retina. With stringent preparation guidelines, the potential risk of transmission of blood-borne diseases is minimized. We review blood-derived products and how they are improving the management of ocular disease.

Keywords: albumin; cryoprecipitate; fibrin glue; fibronectin; fresh frozen plasma; ophthalmology; plasmin; platelet rich plasma; serum; whole blood.

Publication types

  • Review

MeSH terms

  • Albumins / therapeutic use
  • Blood Proteins / therapeutic use*
  • Blood*
  • Diagnostic Techniques, Ophthalmological*
  • Factor VIII / therapeutic use
  • Fibrin Tissue Adhesive / therapeutic use
  • Fibrinogen / therapeutic use
  • Fibronectins / therapeutic use
  • Humans
  • Ophthalmologic Surgical Procedures*
  • Platelet-Rich Plasma

Substances

  • Albumins
  • Blood Proteins
  • Fibrin Tissue Adhesive
  • Fibronectins
  • cryoprecipitate coagulum
  • Factor VIII
  • Fibrinogen