Immunomodulatory Therapy in Uveitis

Dev Ophthalmol. 2016:55:265-75. doi: 10.1159/000431202. Epub 2015 Oct 26.

Abstract

Corticosteroids are the cornerstone of treating intraocular inflammation, but may be inadequate in controlling the disease, or related side effects preclude long-term treatment. Additional immunosuppressive drugs are used in these cases to augment the effect of corticosteroids and allow for their reduction to safe levels while maintaining control of the ocular inflammation. Here we review the different classes of immunosuppressive drugs and discuss their effect on ocular inflammation.

Publication types

  • Review

MeSH terms

  • Glucocorticoids / therapeutic use*
  • Humans
  • Immunomodulation*
  • Immunosuppressive Agents / therapeutic use*
  • Uveitis / drug therapy*

Substances

  • Glucocorticoids
  • Immunosuppressive Agents