Features and perspectives of MR enterography for pediatric Crohn disease assessment

Radiol Med. 2016 May;121(5):362-77. doi: 10.1007/s11547-015-0613-2. Epub 2016 Feb 2.

Abstract

The aim of this paper is to provide indications for performing magnetic resonance enterography (MRE) in Crohn's disease (CD), the essential technical elements of MRE techniques and typical findings in patients with CD. Patients suffering from CD frequently require cross-sectional imaging. By performing MRE, it is possible to obtain results comparable to those obtained with endoscopy in terms of identifying and assessing disease activity and better than other cross-sectional imaging techniques, such as CT, in the evaluation of the fibrosis and complications of disease. The MR imaging of diffusion MR is a technique which enables medical staff to add important additional information and which may replace the use of intravenous contrast agents in the near future. Magnetic resonance enterography is an accurate tool for assessing bowel disease and the various complications associated with CD. The lack of exposure to non-ionizing radiation is an important advantage of this imaging technique, especially in the case of pediatric patients. Familiarity with common and pathognomonic imaging features of CD is essential for every clinician involved in the treatment of inflammatory bowel disease and the care of patients.

Keywords: Crohn’s disease; Diffusion-weighted MRI; MR enterography; Pediatric radiology; Perianal fistula.

MeSH terms

  • Crohn Disease / diagnosis*
  • Diagnosis, Differential
  • Diffusion Magnetic Resonance Imaging / methods
  • Humans
  • Magnetic Resonance Imaging* / methods
  • Predictive Value of Tests
  • Risk Assessment
  • Sensitivity and Specificity
  • Severity of Illness Index

Supplementary concepts

  • Pediatric Crohn's disease