En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography Imaging of Taxane-Associated Cystoid Macular Edema

Ophthalmic Surg Lasers Imaging Retina. 2016 Feb;47(2):176-9. doi: 10.3928/23258160-20160126-12.

Abstract

The taxanes are chemotherapeutic agents that may, in rare cases, cause cystoid macular edema without leakage on fluorescein angiography. Two patients with evidence of taxane-related macular edema presented and were evaluated using novel en face optical coherence tomography (OCT) and OCT angiography (OCTA) imaging modalities. Although OCTA revealed no flow abnormalities in either patient, en face OCT revealed a striking bilateral symmetric cystic tessellation pattern.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Albumins / adverse effects*
  • Antineoplastic Agents, Phytogenic / adverse effects*
  • Female
  • Fluorescein Angiography
  • Humans
  • Macular Edema / chemically induced*
  • Macular Edema / diagnosis*
  • Male
  • Middle Aged
  • Paclitaxel / adverse effects*
  • Pancreatic Neoplasms / drug therapy
  • Tomography, Optical Coherence*
  • Visual Acuity

Substances

  • 130-nm albumin-bound paclitaxel
  • Albumins
  • Antineoplastic Agents, Phytogenic
  • Paclitaxel