The association between multiple sclerosis and uveitis

Tine Gadegaard Olsen; Jette Frederiksen

doi:10.1016/j.survophthal.2016.07.002

The association between multiple sclerosis and uveitis

Surv Ophthalmol. 2017 Jan-Feb;62(1):89-95. doi: 10.1016/j.survophthal.2016.07.002. Epub 2016 Aug 1.

Authors

Tine Gadegaard Olsen¹, Jette Frederiksen²

Affiliations

¹ Department of Neurology, Rigshospitalet-Glostrup, Glostrup, Denmark. Electronic address: tinegadegaard@gmail.com.
² Department of Neurology, Rigshospitalet-Glostrup, Glostrup, Denmark.

PMID: 27491475
DOI: 10.1016/j.survophthal.2016.07.002

Abstract

The association between multiple sclerosis (MS) and uveitis has been questioned. Nerve tissue and eye tissue develop from the same embryonic cells; thus, MS and uveitis could be etiologically associated. In published studies, the prevalence of MS in patients with uveitis differe from 0.7% to 30.4%, whereas the prevalence of uveitis in patients with MS differe from 0.65% to 36.7%. Based on the largest retrospective studies, the prevalence of uveitis among MS patients is ∼1%, and the prevalence of MS among patients with uveitis is ∼1%. This is considerably higher than in the general population; thus, more research on this topic is needed to further understand the relationship between MS and uveitis.

Keywords: autoimmune disease; multiple sclerosis; neurology; ophthalmology; systematic review; uveitis.

Publication types

Review
Systematic Review

MeSH terms

Autoimmunity*
Global Health
Humans
Multiple Sclerosis* / complications
Multiple Sclerosis* / epidemiology
Multiple Sclerosis* / immunology
Prevalence
Uveitis* / epidemiology
Uveitis* / etiology
Uveitis* / immunology