Hot Topics in Retinopathy of Prematurity

Pediatr Ann. 2017 Nov 1;46(11):e415-e422. doi: 10.3928/19382359-20171023-02.

Abstract

Retinopathy of prematurity (ROP) is a condition seen in premature infants that is characterized by abnormal retinal blood vessel growth incited by relative hyperoxia and followed by hypoxia. It can have severe consequences ranging from high myopia to blindness. This article reviews recent "hot" topics related to ROP, specifically the changing incidence of ROP worldwide, the advent of predictive algorithms for screening for ROP, the emerging data behind efficacy of anti-vascular endothelial growth factor treatments for ROP, and advanced retinal imaging in children who were born premature. [Pediatr Ann. 2017;46(11):e415-e422.].

Publication types

  • Review

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use*
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Mass Screening / methods*
  • Retinopathy of Prematurity / diagnosis*
  • Retinopathy of Prematurity / drug therapy
  • Tomography, Optical Coherence / methods
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors

Substances

  • Angiogenesis Inhibitors
  • Vascular Endothelial Growth Factor A