Congenital lymphocytic choriomeningitis virus-an underdiagnosed fetal teratogen

J AAPOS. 2018 Feb;22(1):79-81.e1. doi: 10.1016/j.jaapos.2017.08.011. Epub 2017 Dec 20.

Abstract

Congenital lymphocytic choriomeningitis virus (LCMV) infection is associated with high mortality and morbidity. Although the number of cases reported in the literature has been increasing, it might still be clinically an underdiagnosed human fetal teratogen. We report 2 more cases of serologically proven congenital LCMV infection. One case presented with Aicardi-like syndrome features. Since congenital LCMV infection may mimic Aicardi syndrome, serologic testing should be considered in the workup of patients with Aicardi syndrome to rule out LCMV infection.

Publication types

  • Case Reports

MeSH terms

  • Aicardi Syndrome / diagnosis
  • Child, Preschool
  • Diagnosis, Differential
  • Esotropia / etiology*
  • Female
  • Humans
  • Infant
  • Lymphocytic Choriomeningitis / complications*
  • Lymphocytic Choriomeningitis / congenital
  • Lymphocytic choriomeningitis virus*
  • Male
  • Pregnancy
  • Pregnancy Complications, Infectious / virology
  • Vision Disorders / etiology*