Caruncular Oncocytoma Mimicking Malignant Melanoma

Ocul Oncol Pathol. 2017 Nov;3(4):320-323. doi: 10.1159/000468524. Epub 2017 May 6.

Abstract

Purpose: To report a case of pigmented caruncular oncocytoma that simulated malignant melanoma and discuss the associated ultrasonographic and pathologic features.

Method: Case report.

Results: An 81-year-old female presented with a painless caruncular mass with a smooth brown surface suspicious for melanoma. Ultrasound biomicroscopy revealed a round mass with a large central cavity, more suggestive of a cystic rather than solid lesion. Following complete surgical resection, histopathology revealed a cystadenomatous lesion composed of bland cells with copious eosinophilic cytoplasm consistent with oncocytoma that had a central blood-filled cavity.

Conclusions: Oncocytoma is a benign tumor that can appear pigmented clinically and resemble melanoma. The definitive diagnosis requires histopathologic evaluation. Oncocytoma should be considered in the differential diagnosis of a pigmented caruncular mass.

Keywords: Caruncle; Conjunctiva; Eye; Melanoma; Oncocytoma; Tumor; Ultrasound biomicroscopy.