Relapsing Pityriasis Rosea With HHV-7 Reactivation in an 11-Year-Old Girl

Pediatrics. 2018 May;141(5):e20173179. doi: 10.1542/peds.2017-3179. Epub 2018 Apr 19.

Abstract

Pityriasis rosea (PR) usually presents as acute exanthema with oval erythematous-squamous lesions localized on the trunk, arms, and legs with spontaneous remission. We present an unusual case of PR with frequent relapses during a period of 7 years. An 11-year-old white female patient presented with many pruritic erythematous oval lesions on her trunk. A second episode followed 2 years later with several pruritic erythematous lesions on her lower limbs. During the following 5 years, the patient had several relapses per year, with 1 to 3 lesions on changing localizations. PR was diagnosed on the basis of the clinical presentation and detection of human herpesvirus 7 DNA. Spontaneous remission occurred without treatment in each episode. Relapsing PR is a rare form of PR characterized by a lower number of lesions and smaller sized lesions compared with the classic form of PR. Pediatricians should consider the diagnosis of relapsing PR even if only a single or few erythematous lesions are present.

Publication types

  • Case Reports

MeSH terms

  • Child
  • DNA, Viral / analysis
  • Female
  • Herpesvirus 7, Human / genetics
  • Herpesvirus 7, Human / physiology*
  • Humans
  • Pityriasis Rosea / pathology
  • Pityriasis Rosea / psychology
  • Pityriasis Rosea / virology*
  • Recurrence
  • Remission, Spontaneous
  • Stress, Psychological
  • Virus Activation*

Substances

  • DNA, Viral