Local recurrence of soft-tissue sarcoma: issues in imaging surveillance strategy

Skeletal Radiol. 2018 Dec;47(12):1595-1606. doi: 10.1007/s00256-018-2965-x. Epub 2018 May 21.

Abstract

Soft-tissue sarcomas pose diagnostic and therapeutic challenges to physicians, owing to the large number of subtypes, aggressive tumor biology, lack of consensus on management, and controversy surrounding interval and duration of surveillance scans. Advances in multidisciplinary management have improved the care of sarcoma patients, but controversy remains regarding strategies for surveillance following definitive local control. This review provides an updated, comprehensive overview of the current understanding of the risk of local recurrence of soft-tissue sarcoma, by examining the literature based on features such as histological type and grade, tumor size, and resection margin status, with the aim of helping clinicians, surgeons, and radiologists to develop a tailored approach to local imaging surveillance.

Keywords: Imaging surveillance; Local recurrence; MRI; Musculoskeletal sarcoma; Soft-tissue sarcoma.

Publication types

  • Review

MeSH terms

  • Humans
  • Margins of Excision
  • Neoplasm Grading
  • Neoplasm Recurrence, Local / diagnostic imaging*
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / therapy
  • Neoplasm Staging
  • Population Surveillance
  • Risk
  • Sarcoma / diagnostic imaging*
  • Sarcoma / pathology
  • Sarcoma / therapy
  • Soft Tissue Neoplasms / diagnostic imaging*
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / therapy