Ileocaecal tuberculosis: an under-recognised cause of vitamin B12 deficiency

Ashok Kumar Pannu; Dinesh Raja Palanisamy

doi:10.1177/0049475518816590

Ileocaecal tuberculosis: an under-recognised cause of vitamin B₁₂ deficiency

Trop Doct. 2019 Apr;49(2):143-144. doi: 10.1177/0049475518816590. Epub 2018 Dec 12.

Authors

Ashok Kumar Pannu¹, Dinesh Raja Palanisamy²

Affiliations

¹ 1 Assistant Professor, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
² 2 MD Resident, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

PMID: 30541387
DOI: 10.1177/0049475518816590

Abstract

A combination of anaemia and knuckle pigmentation should always raise concern for megaloblastic anaemia. As the terminal ileum is the site of vitamin B₁₂ absorption and also the commonest site of abdominal tuberculosis, a clinical triad of prolonged fever, knuckle pigmentation and right lower quadrant abdominal tenderness should suggest ileocaecal tuberculosis in endemic areas.

Keywords: Tuberculosis; digestive; disease; physiology.

Publication types

Case Reports

MeSH terms

Adolescent
Anemia, Megaloblastic / complications*
Anemia, Megaloblastic / drug therapy
Anemia, Megaloblastic / pathology
Anemia, Megaloblastic / physiopathology
Antitubercular Agents / therapeutic use
Drug Therapy, Combination
Humans
Ileum / drug effects
Ileum / pathology
Ileum / physiopathology
Male
Treatment Outcome
Tuberculin Test
Tuberculosis, Gastrointestinal / complications*
Tuberculosis, Gastrointestinal / drug therapy
Tuberculosis, Gastrointestinal / pathology
Tuberculosis, Gastrointestinal / physiopathology
Vitamin B 12 / blood
Vitamin B 12 / therapeutic use
Vitamin B 12 Deficiency / drug therapy
Vitamin B 12 Deficiency / etiology*
Vitamin B 12 Deficiency / pathology
Vitamin B 12 Deficiency / physiopathology

Substances

Antitubercular Agents
Vitamin B 12