Staged ocular fornix reconstruction for glaucoma drainage device under neoconjunctiva at the time of Boston type 1 Keratoprosthesis implantation

Ocul Surf. 2019 Apr;17(2):336-340. doi: 10.1016/j.jtos.2019.01.010. Epub 2019 Feb 8.

Abstract

Purpose: Glaucoma is the leading cause of vision loss in eyes with Boston Keratoprosthesis (KPro). Glaucoma drainage devices (GDDs) have been shown to be effective in controlling glaucoma with KPro. Cicatricial conjunctival disease with forniceal shortening is a major challenge and limitation to the use of GDD. In our series, we report the success of fornix reconstruction in cicatricial ocular surface disease as a staged procedure prior to a combined KPro/GDD surgery.

Methods: Retrospective case series involving 4 eyes with surface cicatricization. Three patients with chemical burns and one patient with Ectrodactyly Ectodermal Dysplasia-Clefting syndrome. Preoperative data, surgical interventions, and clinical outcomes were reviewed.

Conclusion: This series represents the first report of fornix reconstruction for combined KPro/GDD surgery. Fornix reconstruction with the aid of AMT with or without OMM grafting is a relatively safe and effective way to manage complex cicatricial surface disease associated with corneal scarring and glaucoma, allowing for subsequent successful implantation of GDD and KPro in cases that were otherwise poor surgical candidates.

Keywords: Boston Keratoprosthesis; Fornix reconstruction; Glaucoma drainage device; Neoconjunctiva.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Artificial Organs*
  • Conjunctiva / surgery*
  • Cornea / surgery
  • Corneal Diseases / complications
  • Corneal Diseases / surgery*
  • Female
  • Glaucoma / complications
  • Glaucoma / physiopathology
  • Glaucoma / surgery*
  • Glaucoma Drainage Implants*
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Implantation / methods*
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity*