Deep Sequencing of Urine Specimens Detects Two BK Polyomavirus Genotypes in a Hematopoietic Stem Cell Transplant Recipient

Trang Dinh Van; Dominic E Dwyer; Neisha Jeoffreys; Jen Kok; Brian J Nankivell; Rebecca J Rockett

doi:10.1128/MRA.01461-19

Deep Sequencing of Urine Specimens Detects Two BK Polyomavirus Genotypes in a Hematopoietic Stem Cell Transplant Recipient

Microbiol Resour Announc. 2020 Jan 30;9(5):e01461-19. doi: 10.1128/MRA.01461-19.

Authors

Trang Dinh Van^{1

2}, Dominic E Dwyer^{2

3}, Neisha Jeoffreys³, Jen Kok³, Brian J Nankivell⁴, Rebecca J Rockett^{2

5}

Affiliations

¹ Clinical Laboratory, National Hospital of Tropical Diseases, Dong Da, Hanoi, Vietnam vandinhtrang.nhtd@gmail.com.
² Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.
³ NSW Health Pathology-Institute of Clinical Pathology and Medical Research, Westmead, NSW, Australia.
⁴ Department of Renal Medicine, Westmead Hospital, Westmead, NSW, Australia.
⁵ Centre for Infectious Diseases and Microbiology-Public Health, Sydney, NSW, Australia.

Abstract

BK polyomavirus (BKPyV) is an important pathogen in transplant recipients. We report four draft BKPyV genomes, three of BKPyV genotype I (subtype I-b2) (AUS-105, AUS-106, and AUS-108) and one of genotype II (AUS-107). These draft genomes were identified in longitudinal urine samples collected from a single hematopoietic stem cell transplant recipient.