Comparison of various surgical techniques for optic disc pit maculopathy: vitrectomy with internal limiting membrane (ILM) peeling alone versus inverted ILM flap 'plug' versus autologous scleral 'plug'

Br J Ophthalmol. 2020 Nov;104(11):1567-1573. doi: 10.1136/bjophthalmol-2019-315075. Epub 2020 Feb 6.

Abstract

Aim: To compare the anatomical and visual outcomes of vitrectomy with internal limiting membrane (ILM) peeling alone versus inverted ILM flap to plug the pit versus autologous scleral plug for the treatment of optic disc pit maculopathy (ODP-M).

Methods: This retrospective study included 23 patients (23 eyes) who underwent 25G pars plana vitrectomy, ILM peeling and gas tamponade. While the pit was not plugged in group 1 (n=8), inverted ILM flap and autologous scleral flap were used to plug the pit in group 2 (n=7) and group 3 (n=8), respectively. Complete anatomical success was defined as total resolution of subretinal fluid (SRF) and macular schisis on optical coherence tomography while visual success was defined as a gain of at least 2 Snellen lines 1 year after surgery.

Results: Baseline characteristics were similar in all three groups. Mean central foveal thickness and SRF decreased in all three groups (p<0.05). Complete anatomical success was achieved in 25.0%, 85.7% and 87.5% eyes while visual success was achieved in 12.5%, 28.6% and 12.5% eyes in groups 1, 2 and 3, respectively. One eye (4.3%) in group 2 developed full-thickness macular hole at 1 month post-surgery. After complete resolution, there was no recurrence of fluid.

Conclusion: OPD-M has a better surgical outcome if the pit is plugged. Both inverted ILM flap and autologous scleral plug are equally efficacious adjuncts to plug the pit.

Keywords: ILM flap; ILM peeling; Macular hole; optic disc pit maculopathy (ODPM); outer retinal hole (ORH); scleral plug.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Basement Membrane / surgery*
  • Endotamponade
  • Eye Abnormalities / diagnostic imaging
  • Eye Abnormalities / physiopathology
  • Eye Abnormalities / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Ophthalmologic Surgical Procedures
  • Optic Disk / abnormalities*
  • Retinal Detachment / diagnostic imaging
  • Retinal Detachment / physiopathology
  • Retinal Detachment / surgery*
  • Retrospective Studies
  • Sclera / surgery*
  • Subretinal Fluid
  • Suction
  • Surgical Flaps*
  • Tomography, Optical Coherence
  • Visual Acuity / physiology
  • Vitrectomy / methods*
  • Young Adult