Angiographic findings and outcomes after embolization of patients with suspected postabortion uterine arteriovenous fistula

J Gynecol Obstet Hum Reprod. 2021 Sep;50(7):102033. doi: 10.1016/j.jogoh.2020.102033. Epub 2020 Dec 7.

Abstract

Introduction: The purpose of this study is to assess the angiographic incidence of uterine arteriovenous fistula (UAVF) in women referred for a high ultrasonographic suspicion in a postabortion setting and to evaluate the safety, efficacy and impact on further fertility of uterine artery embolization (UAE) in this indication.

Materials and methods: A monocentric retrospective study of 31patients managed by uterine artery embolization for suspected UAVF after spontaneous or induced first trimester abortion. The diagnosis of UAVF was confirmed when an early venous drainage was identified on the angiogram. Technical success was defined as complete exclusion of the vascular lesion. Clinical success was defined as the absence of bleeding during the clinical follow-up and during the surgery in case of hysteroscopic resection. Information about further fertility was gathered by phone calls to the patients.

Results: The mean age of the patients was 30.8 (±6.0) years. The diagnosis of UAVF was angiographically confirmed in 6 patients (19.4 %). Angiographic findings of retained product of conception (RPOC) with varying degrees of vascularity were observed in remaining patients. The technical success rate of UAE was 100 %, mostly through a proximal and bilateral embolization using a resorbable agent (27/31 patients, 87.1 %). The clinical success rate of UAE was 100 % in the group treated by a single UAE. We did not notice any bleeding during the surgery in the group of patients who needed a further hysteroscopic resection. 14 patients led at least one subsequent pregnancy to term without any difficulty.

Conclusion: UAVF is a rare condition. We supposed it may constitute the ultimate stage in the natural history of the retained products of conception with "marked vascularity". UAE seems to be an effective and safe first-line treatment.

Keywords: Arteriovenous fistula; Postpartum haemorrhage; Uterine artery embolization.

MeSH terms

  • Abortion, Induced / adverse effects*
  • Abortion, Induced / methods
  • Adult
  • Angiography / methods*
  • Angiography / statistics & numerical data
  • Arteriovenous Fistula / diagnosis*
  • Arteriovenous Fistula / diagnostic imaging
  • Embolization, Therapeutic / methods*
  • Embolization, Therapeutic / statistics & numerical data
  • Female
  • Humans
  • Pregnancy
  • Retrospective Studies
  • Uterus / abnormalities
  • Uterus / diagnostic imaging*