Abstract
Two patients with Acanthamoeba keratitis developed a corneal abnormality following prolonged treatment with topical 0.1% [corrected] propamidine isethionate. In both instances, withdrawal of drug therapy resulted in a gradual clearing of the keratopathy, with no permanent sequelae. The changes we observed may be confused with those of active Acanthamoeba infection.
Publication types
-
Case Reports
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Acanthamoeba
-
Administration, Topical
-
Adult
-
Amebiasis / drug therapy
-
Amidines / adverse effects*
-
Animals
-
Benzamidines / administration & dosage
-
Benzamidines / adverse effects*
-
Benzamidines / therapeutic use
-
Corneal Diseases / chemically induced*
-
Corneal Diseases / pathology
-
Cysts / chemically induced
-
Female
-
Humans
-
Keratitis / etiology
-
Male
Substances
-
Amidines
-
Benzamidines
-
propamidine isethionate